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Evaluation of calcium ion release in calcium hydroxide prototype as intracanal medicament

  • Atia N. Sidiqa ,
  • Myrna N. Zakaria ,
  • Ira Artilia ,
  • Zwista Y. Dewi ,
  • Arief Cahyanto ,

Abstract

Objective:Calcium Hydroxide (Ca(OH)2 ) has been widely used in many dental treatments such as pulp capping, dentin hypersensitivity and as an endodontic intracanal medicament. Ca(OH)2 is highly alkaline, has antimicrobial, and remineralization action by releasing Ca2+ and OH. Ca2+ release plays an important role in cell proliferation and remineralization of hard tissue healing. Indonesian limestone can be synthesized to produce Ca(OH)2 that can be an alternative to commercial Ca(OH)2 available. Therefore this study aimed to synthesized a Ca(OH)2 prototype and evaluate the Ca2+ released by the Ca(OH)2 prototype.Material and Methods: Ca(OH)2 prototype was synthesized from limestone by calcination process and characterized by XRD and FTIR. The Ca(OH)2 prototype was then manipulated to a pasta form by mixing the powder with distilled water in 0.8 w/p ratio then inserted to a polyethylene tubed (2x10mm) using and immersed in 10 ml distilled water. Samples were divided into three groups for different periods of Ca2+ evaluation (1, 7 and 14 days). The Ca2+ concentration released was measured by a Spectrophotometer (DIRUI DR-7000D). Data obtained were analyzed by Anova.Results: The observations on one day immersion was 3.589 mg/dL, the observation for seven days was 3.736 mg/dL, and for 14 days was 3.850 mg/dL. Statistically p<0.05.Conclusion: Calcium hydroxide prototype released a sustainable amount of Ca2+ up to 14 days with the highest concentration achieved on day 14th.
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References

  1. Fulzele P, Baliga S, Thosar N, et al. Evaluation of calcium
  2. ion, hydroxyl ion release and pH levels in various calcium
  3. hydroxide based intracanal medicaments: An in vitro
  4. study. Contemp Clin Dentist 2011;2: 291-295.
  5. Hargreaves KM, Berman LH. Cohen pathway of the pulp.
  6. th ed. St Louis United Kingdom: Elsevier; 2016. p. 459.
  7. Kawashima N, Wadachi R, Suda H, et al. Root canal
  8. medicaments. J International Dental 2009;59: 5-11.
  9. Kim D, Kim E. Antimicrobial effect of calcium hydroxide
  10. as an intracanal medicament in root canal treatment: a
  11. literature review-part I. in vitro studies, Restor. Dent Endod
  12. ;39: 241-252.
  13. Moazami F, Sahebi S, Jamshidi D, et al. The long-term
  14. effect of calcium hydroxide, calcium-enriched mixture
  15. cement and mineral trioxide aggregate on dentin strength.
  16. J Iranian Endodontic 2014;9: 185-189.
  17. Zahid S, Qadir S, Saeed A, et al. The influence of moisture
  18. on the setting time of the latest commercially available
  19. calcium hydroxide cements; a clear guideline for the
  20. dentist. Pakistan Oral & Dent J 2016;36: 691-696.
  21. Komabayashi T, D’Souza RN, Dechow PC, et al. Particle
  22. size and shape of calcium hydroxide. JOE 2009;35: 284-287.
  23. Sidiqa AN. Biomimetics in dental materials. J Material
  24. Kedokteran Gigi 2013;2: 1-8. (In Indonesian)
  25. Zakaria MN, Sidiqa AN, Artilia I, et al. Synthesis and
  26. characterization of calcium hydroxide from indonesian
  27. limestone as endodontic intracanal medicament. KEM
  28. ;782: 268-272.
  29. Chaudhari WA, Jain RJ, Jadhav SK, et al. Calcium ion
  30. release from four different lightcured calcium hydroxide
  31. cements. Endodontol 2016;28: 114-118.
  32. Srinivas S, Jibhkate NG, Baranwal R, et al. Propylene
  33. glycol: a new alternative for an intracanal medicament. J
  34. Int Oral Health 2016;8: 611-614.
  35. Zakaria MN. Save the pulp is the essential issues on pulp
  36. capping treatment, J Dentomaxillofac Sci 2016;1: 73-76.
  37. Komabayashi T, D’Souza RN, Dechow PC, et al. Particle
  38. size and shape of calcium hydroxide. JOE 2009;35: 284-287.
  39. Carré E, Pérot J, Jauzein V, et al. Estimation of water quality
  40. by UV/Vis spectrometry in the framework of treated
  41. wastewater reuse. Water Sci Technol 2017;76: 633-641.
  42. Behera S, Ghanty S, Ahmad F, et al. UV-Visible spectrophotometric method development and validation of assay
  43. of paracetamol tablet formulation. J Int Chemical Analytic
  44. Sci 2012;3: 1656-1661.
  45. Grover C, Shetty N. Evaluation of calcium ion release and
  46. change in pH on combining calcium hydroxide with different
  47. vehicles. Contemp Clin Dentist 2014;5: 434-439.
  48. Misra P, Bains R, Loomba K, et al. Measurement of ph
  49. and calcium ions release from different calcium hydroxide
  50. pastes at different intervals of time: atomic spectrophotometric analysis. J Oral Biol Craniofas Res 2017;7: 36-41.
  51. Zakaria MN, Cahyanto A, El-Ghannam A. Calcium
  52. release and physical properties of modified carbonate apatite
  53. cement as pulp capping agent in dental application.
  54. Biomater Res 2018;22: 35.
  55. Jain A, Bhadoria K, Hada HS. Spectrophotometric
  56. evaluation of calcium ion release from different calcium
  57. hydroxide preparations: An in-vitro study. J Oral Res
  58. ;6: 61-63.
  59. Athanassiadis B, Walsh LJ. Aspects of solvent chemistry
  60. for calcium hydroxide medicaments. Materials (Basel)
  61. ;23: 10.
  62. Teoh Y, Athanassiadis B, Walsh LJ. The influence of
  63. aqueous and PEG 400 solvent vehicles on hydroxyl ion
  64. release from calcium hydroxide medicaments. Int DentistAfrican Ed 2017;7: 30-40.
  65. Fava LRG, Saunders WP. Calcium hydroxide pastes:
  66. classification and clinical indications. Int Endod J
  67. ;32: 257-282.
  68. Nugroho JJ. One versus two visits of endodontic treatment
  69. on teeth with apical periodontitis. J Dentomaxillofac Sci
  70. ;1: 77-79.

How to Cite

Sidiqa, A. N., Zakaria, M. N., Artilia, I., Dewi, Z. Y., & Cahyanto, A. (2020). Evaluation of calcium ion release in calcium hydroxide prototype as intracanal medicament. Journal of Dentomaxillofacial Science, 5(2), 86–89. https://doi.org/10.15562/jdmfs.v0i0.1017

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