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Increase in alp levels at odontoblast cell line after haruan (Channa striata) extract administration as remineralization material


Objective: To determine the effectivity of haruan (Channa striata) extract which added calcium hydroxide to ALP levels in odontoblast cell line.                                   Material and Methods: The study used a posttest only control group design. Odontoblast MDPC-23 cell line that has been distributed in 96-well microplates is divided into 8 groups. ALP levels were measured by ELISA reader. Data were analyzed statistically using ANOVA statistical test, followed by Bonferroni's post test.Results:The ALP level in the odontoblast cell line in haruan extract that added with calcium hydroxide increased compared to the control. At a concentration of 25 µg/ml = 208.37 µg/ml, a concentration of 50 µg/ml = 219.04 µg/ml, a concentration of 100 µg/ml = 282.93 µg/ml and differed significantly from the control group.Conclusion:The effect of haruan extract added with calcium hydroxide can increase the ALP level in odontoblast cell line as concentration increases.


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How to Cite

Nugroho, J. J. (2022). Increase in alp levels at odontoblast cell line after haruan (Channa striata) extract administration as remineralization material. Journal of Dentomaxillofacial Science, 7(1), 54–56.




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