Correlation between periodontal disease and COVID-19: Systematic review and meta-analysis

Abstract

Objective: The purpose of this systematic review was to overview studies related to the relationship between periodontitis and the severity of COVID-19. Method: This systematic review and meta-analysis aims to see an overview of studies related to the relationship between periodontal disease and the severity of COVID-19, especially hospitalization. From the systematic review, 12 pieces of literature are included in the eligibility criteria and analyzed (9 reviews and three meta-analyses). Results: The estimated OR is 2.68 (z test p = 0.006), moderate heterogeneity is 61%. The periodontal treatment for patient COVID-19 were considered to prevent the death and severity of COVID-19. Conclusion: Periodontal disease had been associated with the severity and mortality of COVID-19, even though the further studies are needed to generalize to other populations. Apart, we hope that COVID-19 patients, get more attention for their periodontal tissue conditions, in order to prevent the death and severity of these patients.