The effect of chlorhexidine and triclosan on undisturbed plaque formation for 72 hours duration
Abstract
Plaque control is the main method for preventing periodontal diseases. Chlorhexidineia a gold standard mouthrinse but it has a side effect which limits its use. Triclosanwhich does not have side effects was used to evaluate its efficacy againstchlorhexidine. This experiment aimed to evaluate the effect of chlorhexidine andtriclosan on undisturbed plaque formation for 72 hours. Two groups, chlorhexidineand triclosan, respectively consists of 14 volunteers refrained from all mechanicaloral hygiene measures for the following 72 hours and rinsed instead twice daily for 1minute with 15 mL of either chlorhexidine or triclosan. The plaque accumulation wasassessed after 24, 48 and 72 hours using Modified Quigley-Hein Score. The medianplaque score between both groups on day 1 was not significantly different (p= 0.625),but the score on day 2 and day 3 were significantly different (p= 0.007 and 0.017respectively). The score between day 1 and day 3 on subjects using chlorhexidine wasnot significantly different (p= 0.109) unlike on subjects using triclosan (p= 0.003).The conclusion was chlorhexidine is more effective in controlling plaque formationcompared to triclosan.
Section
References
- Quirynen MT, Haake SK, Newman MG. Microbiology of periodontal diseases. In: Newman MG, Takei HH, Klokkevold PR, Carranza FA, editors. Carranza’s clinical periodontology, 10th ed. Philadelphia: W.B. Saunders Company; 2006. p. 134-49.
- Sreenivasan P, Gaffar A. Antiplaque biocides and bacterial resistance: a review. J Clin Periodontol 2002; 29 (11): 965-74. 3. Fernandes Naglik L, Downes J, Shirlaw P, Wilson R, Challacombe SJ, Kemp GK, et al. The clinical and microbiological effects of a novel acidified sodium chlorite mouthrinse on oral bacterial mucosal infections. Oral Dis 2001; 7 (5): 276-80.
- Franco CF, Pataro AL, Santos VR, Cortes ME, Sinisterra RD. In vitro effects of a chlorhexidine controlled delivery system. Artif Organs 2003; 27 (5): 486-91. 5. Willmann DE, Nield-Gehrig JS. The dental plaque biofilm: Foundations of periodontics for the dental hygienist. Lippincott; 2003.
- Quigley GA, Hein JW. Comparative cleansing efficiency of manual and power brushing. J Am Dent Assoc 1962; 65: 26-9.
- Arweiler NB, Henning G, Reich E, Netuschil L. Effect of an amine-fluoride-triclosan mouthrinse on plaque regrowth and biofilm vitality. J Clin Periodontol 2002;29(4):358-63.
- Sekino S, Ramberg P, Uzel NG, Socransky S, Lindhe J. Effect of various chlorhexidine regimens on salivary bacteria and de novo
- plaque formation. J Clin Periodontol 2003; 30 (10): 919-25.
- Keijser JA, Verkade H, Timmerman MF, Van der Weijden FA. Comparison of 2 commercially available chlorhexidine mouthrinses. J Periodontol 2003;74(2): 214-8.
- Greene JC. The oral hygiene indexdevelopment and uses. J Periodontol 1967; 38 (6): Suppl: 625-37.
- Rustogi KN, Curtis JP, Volpe AR, Kemp JH, McCool JJ, Korn LR. Refinement of the modified navy plaque index to increase plaque scoring efficiency in gumline and interproximal tooth areas. J Clin Dent 1992; 3 (Suppl C): C9-12.
How to Cite
Arief, E. M., Binti Adnan, N. D., & Raja Awang, R. A. (2010). The effect of chlorhexidine and triclosan on undisturbed plaque formation for 72 hours duration. Journal of Dentomaxillofacial Science, 9(1), 1–6. https://doi.org/10.15562/jdmfs.v9i1.225