Case Report

Penatalaksanaan kandidiasis oral disebabkan Candida tropicalis pada anak dengan gangguan sistemik

Cane Lukisari , Dwi Setyaningtyas, Mintarsih Djamhari

Cane Lukisari
Ilmu Penyakit Mulut Fakultas Kedokteran Gigi Universitas Airlangga Surabaya, Indonesia. Email:

Dwi Setyaningtyas
Bagian Penyakit Mulut, Rumah Sakit Angkatan Laut dr. Ramelan Surabaya, Indonesia

Mintarsih Djamhari
Departemen Ilmu Penyakit Mulut Fakultas Kedokteran Gigi Universitas Airlangga Surabaya, Indonesia
Online First: October 30, 2010 | Cite this Article
Lukisari, C., Setyaningtyas, D., Djamhari, M. 2010. Penatalaksanaan kandidiasis oral disebabkan Candida tropicalis pada anak dengan gangguan sistemik. Journal of Dentomaxillofacial Science 9(2): 78-85.

Oral candidiasis is an oral mucosal infection caused by Candida albicans (CA) or
non-Candida albicans Candida (NCAC). C. tropicalis (CT) is most virulent NCAC
because it has the most adherence ability to epithelial cells in vitro as well as medium
level proteinase secretion. In addition, CT is the second most common colony found in
human. Although incidence rate of oral infection was low, this species has virulence
potency, lately reported as the mayor cause of candidemia in immunocompromised
patients. This paper reports and discusses oral candidiasis due to CT in a child who
suffered anemia with clinical sign of malnutrition. Oral nystatin suspension is therapy
of choice because of patient well response, and in vitro studies reported lack of
response of fluconazole to candidemia due to C.tropicalis. However, nystatin oral
suspension, should be synchronized with hygiene optimalization of elimination of
predisposition factors, and supportive therapy would provide a good prognosis.


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