Original Article

Efektivitas hyaluronic acid 0,1% terhadap penyembuhan luka trauma akibat piranti ortodontik cekat Effectivity of 0.1% hyaluronic acid toward to healing of trauma injury due to fixed orthodontics

Hanna Silvia Debora , Nada Ismah, Benny Mulyono Soegiharto

Hanna Silvia Debora
Departemen Ortodontik Fakultas Kedokteran Gigi, Universitas Indonesia Jakarta, Indonesia. Email: nadalukman@yahoo.com

Nada Ismah
Departemen Ortodontik Fakultas Kedokteran Gigi, Universitas Indonesia Jakarta, Indonesia

Benny Mulyono Soegiharto
Departemen Ortodontik Fakultas Kedokteran Gigi, Universitas Indonesia Jakarta, Indonesia
Online First: February 28, 2012 | Cite this Article
Debora, H., Ismah, N., Soegiharto, B. 2012. Efektivitas hyaluronic acid 0,1% terhadap penyembuhan luka trauma akibat piranti ortodontik cekat Effectivity of 0.1% hyaluronic acid toward to healing of trauma injury due to fixed orthodontics. Journal of Dentomaxillofacial Science 11(1): 7-13.


Treatment with a fixed orthodontic aims to improve malocclusion and enhance the aesthetic. Traumatic injury to the
mucosa of the mouth is one of the risks that often occur and can be addressed among others by using mouthwash
that contains hyaluronic acid. This study aimed to determine the effectiveness of 0.1% hyaluronic acid on wound
healing caused by trauma of fixed rthodontic appliance in terms of size wound, redness and pain. Twenty two
patients who had a traumatic injury caused by fixed appliance on buccal or labial mucosa were divided into 2
groups: K1, was instructed to rinse 10 ml solution containing 0.1% hyaluronic acid for 2 minutes after brushing
teeth, 2 times a day for 4 days; K2, used the K1’s instruction but using a placebo solution. Examination of size are
used caliper and reddish wounds are used index measuring wound redness performed before and after treatment,
and pain measurement used questionnaires. Based on the statistical analysis of t-test, the percentage of size changes
and redness traumatic injury were more significant in K1 than in K2 (p<0.05). While the pain of traumatic changes
in K1 than in K2 were not significant (p>0.05). The use of mouthwash containing 0.1% hyaluronic acid was
concluded proved effective to accelerate the wound healing process, but does not prove effective reducing pain
caused by traumatic injury due to fixed orthodontic appliance.

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