Original Article

Hubungan antara level estradiol dan progesterone dengan stomatitis aftosa rekuren Relation between estradiol and progesterone hormone level with recurrent aphthous stomatitis

Sumintarti Sumintarti , Erni Marlina

Sumintarti Sumintarti
Bagian Oral Medicine Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, Indonesia. Email: mien.sugiharto@yahoo.com

Erni Marlina
Bagian Oral Medicine Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, Indonesia
Online First: October 30, 2012 | Cite this Article
Sumintarti, S., Marlina, E. 2012. Hubungan antara level estradiol dan progesterone dengan stomatitis aftosa rekuren Relation between estradiol and progesterone hormone level with recurrent aphthous stomatitis. Journal of Dentomaxillofacial Science 11(3): 137-141.


Recurrent aphthous stomatitis (RAS) is a common inflammatory oral disease. The etiology remains unclear; however
some studies and case reports showed any association between estradiol and progesteron level in this disease. The aim
of this article is to evaluate estradiol and progesteron level in RAS subjects. Purposive sampling was used in this study
with 15 total subjects. Phase of luteal and ulcer reccurence characteristic are based on quisioner data. Estradiol and
progesterone level is examined by vena serum. Only one sample (6.7%)showed higher estradiol level than normal and
the rest (93.3%) are in normal level. Contrastly, 3 samples (20%)were in normal for progesterone level, while the
others, 12 samples (80%)were in low level. Estradiol level in RAS subjects tend to normal range, while progesterone
levels tend to be low

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