Original Article

Efektivitas ekstrak metanol batang pisang mauli 100%padapenyembuhan luka punggung mencit (Mus musculus)ditinjau dari jumlah sel radang (Effectiveness of 100%extract of Mauli Banana stem to healing process of mice’s (Mus musculus)back from the perspective of the number of inflamed cell)

Maharani Laillyza Apriasari , Amy Nindia Carabelly, Gusti Febby Aprilia

Maharani Laillyza Apriasari
Program Studi Kedokteran Gigi Fakultas Kedokteran Universitas Lambung Mangkurat Banjarmasin, Indonesia. Email: maharaniroxy@gmail.com

Amy Nindia Carabelly
Program Studi Kedokteran Gigi Fakultas Kedokteran Universitas Lambung Mangkurat Banjarmasin, Indonesia

Gusti Febby Aprilia
Program Studi Kedokteran Gigi Fakultas Kedokteran Universitas Lambung Mangkurat Banjarmasin, Indonesia
Online First: February 28, 2014 | Cite this Article
Apriasari, M., Carabelly, A., Aprilia, G. 2014. Efektivitas ekstrak metanol batang pisang mauli 100%padapenyembuhan luka punggung mencit (Mus musculus)ditinjau dari jumlah sel radang (Effectiveness of 100%extract of Mauli Banana stem to healing process of mice’s (Mus musculus)back from the perspective of the number of inflamed cell). Journal of Dentomaxillofacial Science 13(1): 33-37. DOI:10.15562/jdmfs.v13i1.384


Banana plant especially its trunk contains many kinds of fitokimia such as saponin, flavonoid, and tannin which
function as antibiotic and fasten the healing process. Mauli banana stem extract is often used by the people in Hulu
Sungai Utara Banjarmasin Province to fasten healing skin injury. The purpose of this research is to histopathologically
examine the effectiveness of Mauli Banana stem extract to the healing process of the mice’s back (Mus musculus)on
the 3rd day. This purely true experimental research with post test only with control design used 27 mices which were
divided to 3 groups. Treatment group was given methanol extract of mauli banana stem whose average scores of
neutrofil and macrofag are representatively 2.333 and 1; negative control group was given aquadest with its average
neutrofil and macrofag scores are representatively 1.055 dan 1.678; and positive control group was given standard
medicine which contained Aloe veraextract with its average neutrofil and macrofag scores are representatively 1.066
dan 1.667. The result of Kruskall-Wallis and Mann-Whiney showed a significant difference between treatment group
and negative control group. It can be concluded that the extract methanol of mauli banana stem on the healing process
of injury to mancit’s back histopathologically influences the decreasing acute inflamed (neutrofil) cell and the
increasing chronic inflamed (macrophage) cell on the third day. In this case the extract of mauli banana stem is
medically potential to fasten the healing process of injury.

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