Original Article

Ekstrak ikan haruan (Channa striata) meningkatkan jumlah neokapiler pada penyembuhan luka (Extract of haruan (Channa striata) increases neocapillaries count in wound healing process )

Muhammad Reza Setiawan , Nurdiana Dewi, Ika Kustiyah Oktaviyanti

Muhammad Reza Setiawan
Program Studi Kedokteran Gigi Universitas Lambung Mangkurat Banjarmasin, Indonesia. Email: rezaasetiawan@gmail.com

Nurdiana Dewi
Bagian Biologi Oral, Program Studi Kedokteran Gigi Universitas Lambung Mangkurat Banjarmasin, Indonesia

Ika Kustiyah Oktaviyanti
Bagian Patalogi Anatomi, Fakultas Kedokteran Universitas Lambung Mangkurat Banjarmasin, Indonesia
Online First: February 28, 2015 | Cite this Article
Setiawan, M., Dewi, N., Oktaviyanti, I. 2015. Ekstrak ikan haruan (Channa striata) meningkatkan jumlah neokapiler pada penyembuhan luka (Extract of haruan (Channa striata) increases neocapillaries count in wound healing process ). Journal of Dentomaxillofacial Science 14(1): 1-5. DOI:10.15562/jdmfs.v14i1.416


Haruan is Kalimantan’s indigenous fish which has the potency to accelerate wound healing. Haruan extract has
substantial properties such as albumin, Zn,Cu, and Feto accelerate wound healing. The purpose of this study is to assess
the effect of haruan extract on wistar rats buccal mucosa wound healing on day 1, 3, 5, and 7 histopathologically. This
study was purely experimental with pretest-posttest with control group design. Samples were divided into 4 treatment
groups, haruan extract 25%, 50%, 100% treatment groups and aquadest treatment group as negative control, each
treatment wasperformed for 7 days. Neocapillariescount reached its peak on day 5. Mean neocapillaries scoring of each
group was 12, 16.5, 18.5, 6 respectively. Two way Anova and post hoc LSD tests presented a significant difference
between negative control and haruan extract groups. In conclusion, haruan extract treatment significantly increased
neocapillaries count in wound healing process.

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