Original Article

The Prevalence of xerostomia occurrence after doing radiation therapy in patients with head and neck cancer

Barunawaty Yunus

Barunawaty Yunus
Department of Dental Radiology, Faculty of Dentistry, Hasanuddin University Makassar, Indonesia. Email: barunawaty@yahoo.com
Online First: April 01, 2017 | Cite this Article
Yunus, B. 2017. The Prevalence of xerostomia occurrence after doing radiation therapy in patients with head and neck cancer. Journal of Dentomaxillofacial Science 2(1): 13-17. DOI:10.15562/jdmfs.v2i1.459

Xerostomia is one side effect of radiation therapy that most commonly affects head and neck. This situation is a symptom and not a disease which is generally associated with reduced saliva. For patients this situation is not pleasant and for dentist, this symptom is considered as a challenging case. This research intended to know the prevalence of xerostomia after radiation therapy in cancer patients with head and neck area. The subjects of this study were patients with head and neck area cancer who underwent radiotherapy treatment at Hasanuddin University teaching hospital, subjects were then taken saliva before and after given a total dose of 20 Gy and a total dose of 40 Gy. The analysis of the data processed by the computer program and the Wilcoxon test significance level is accepted when p<0.05. The mean bulk saliva before radiotherapy was higher than average rainfall saliva after radiotherapy total dose of 20 Gy and 40 Gy. Radiotherapy of the head and neck area total dose of 20 Gy and 40 Gy may affect rainfall saliva so that patients feel the symptoms of xerostomia.


Rasad S. Radiologi diagnostik. 2nd ed. Jakarta: Balai Penerbit FKUI; 2010. p. 1- 26.

Burket LW, Greenberg MS, Glick M, et al. Oral cancer. In: Epstein J, Wall IVD. Editors. Burket's oral medicine: diagnosis and treatment. 10th ed. Philadhelpia: J.B.Lippincott Co; 2008. p. 194-226.

Susworo R. Radioterapi : dasar-dasar radioterapi dan tata laksana radioterapi penyakit kanker. Jakarta: Penerbit Universitas Indonesia; 2007. p. 1-78.

Moller PPM, Ozsahin M, Monnier P. A prospective study of salivary gland function in patient undergoing radiotherapy for squamous cell Carcinoma of the Oropharynx. 2004 [cited 2011 Dec 11]; Available from: http://www.ncbi.nlm.nih.gov/pubmed/14970776.

Rini E. Xerostomia sebagai salah satu efek samping terapi radiasi. USU e-Repository 2005.

Agustin RN. Pengaruh radioterapi area kepala dan leher terhadap perbedaan Curah Saliva pria dan wanita. Yogyakarta: Fakultas Kedokteran Gigi Universitas Gadjah Mada; 2006.

Fithrony M. Pengaruh radioterapi area kepala dan leher terhadap Curah Saliva. Semarang: Universitas Diponegoro; 2012.

Meidyawati R. Pengaruh radiasi dosis terapi terhadap kekerasan email yang dilapisi Varnish Fluor. Jakarta; Indonesia University; 2003.

Amerongen AVN. Ludah dan kelenjar ludah: arti bagi kesehatan gigi. Yogyakarta: Gadjah Mada University Pers. p. 1-39.

Andrews N, Griffiths C. Dental Complications of Head and Neck Radiotherapy: Part 1. Aust Dent J. 2001;46: 88-94.

No Supplementary Material available for this article.
Article Views      : 884
PDF Downloads : 487

Related Articles

Search Authors in

  • Barunawaty Yunus

  • Barunawaty Yunus

  • Barunawaty Yunus