Original Article

Effect of mangrove leaves extract (avicennia marina) concentration to streptococcus mutans and candida albicans growth

Mohammad Dharmautama , Richard Tetelepta, Muhammad Ikbal, Andi EA. Warti

Mohammad Dharmautama
Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia. Email: richardtetelepta@ymail.com

Richard Tetelepta
Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Muhammad Ikbal
Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Andi EA. Warti
Department of Prosthodontic, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Online First: December 01, 2017 | Cite this Article
Dharmautama, M., Tetelepta, R., Ikbal, M., Warti, A. 2017. Effect of mangrove leaves extract (avicennia marina) concentration to streptococcus mutans and candida albicans growth. Journal of Dentomaxillofacial Science 2(3): 155-159. DOI:10.15562/jdmfs.v2i3.648


Objective: This study aims to determine the effect of mangrove leaves extract (avicennia marina) concentration to streptococcus mutans and candida albicans growth which is commonly found in removable denture plate.

Material and Methods: Production of mangrove leaves extract (avicennia marina) used 96% ethanol solution. Mangrove leaves extract was prepared at a concentration of 2.5%, 5%, 7.5%, 10% and controlled with denture cleanser materials available in the market. Furthermore, the bacteria activity of streptococcus mutans and candida albicans (ATCC 10231) were tested, then the data were analyzed by One Way ANOVA and Post Hoc Test (Tukey HSD).

Results: Statistical analysis of mangrove leaves extract with 2.5% concentration (6.850 ± 0.127), 5% (7.185 ± 0.007), 7.5% (8.360 ± 0.283), 10% (8.485 ± 0.219) and positive control (9.060 ±0.226), showed significant inhibition zone differences (p<0.05). The concentration of 7.5% had optimal inhibition growth of streptococcus mutans (p<0.05). Mangrove leaves extract to 10% concentration had not shown the effects of inhibition zone against candida albicans.

Conclusion: Mangrove leaves extract (avicennia marina) is effective to inhibit the growth of streptococcus mutans but hasn’t shown inhibition zone against candida albicans until 10% concentration

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