Skip to main content Skip to main navigation menu Skip to site footer

Salivary pH changes post nasopharyngeal carcinoma radiotherapy using linac x- ray

  • Azhari Azhari ,
  • Yohanes Hutasoit ,
  • Ary C. Permana ,
  • Setiawan Soetopo ,


Abstract

Objective: The purpose of this study was to obtain an illustration of saliva pH in patients undergoing radiotherapy with linac x-ray radiation for nasopharyngeal carcinoma. Radiation therapy for nasopharyngeal carcinoma frequently caused severe salivary gland dysfunction. The salivary gland dysfunction possibly influenced saliva pH.Material and Methods: The study was a simple descriptive. This study was conducted on 7 males and 2 females undergoing radiation therapy with linac x-ray for nasopharyngeal carcinoma. The measurement of saliva pH was done using an electrode pH meter.Results: This study shows that the range of saliva pH in 9 patients undergoing radiation therapy is 5.34 to 6.19.Conclusion: That saliva pH in 9 patients undergoing radiation therapy with linac x-ray radiation for nasopharyngeal carcinoma at Dr. Hasan Sadikin Hospital is lower than its normal value.
Keywords: Saliva pH Nasopharyngeal carcinoma Linac x-ray radiation
Section

References

  1. Larry CC,Gerald FC, Bruce WT, et al. Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skina randomized controlled trial. JAMA 1996;276: 1957-1963.
  2. Noegroho HSY, Subita GP. Mempertahankan kualitas hidup pasien yang menjalani radioterapi pada kepala dan leher, JKGUI (Edisi khusus) 2003;10: 260-265.
  3. Susworo R. Kankernasofaring: epidemiologi dan pengobatan mutakhir. Cermin Dunia kedokteran 2004;144: 16-18.
  4. Stephen WK, Cheng MS, Albert CW, etal. Carotid s tenosis after radiotherapy for nasopharyngeal carcinoma. Arch Otolaryngol Head Neck Surg 2000;126: 517-521.
  5. Sabrina S, Azhari A, Dudi A. DMF-T index in patients undergoing radiation therapy with LINAC X-ray radiation for head and neck cancer at Department of Radiotherapy, Dr. Hasan Sadikin Hospital. J Dent 2007;19: 156-161.
  6. Vissink A, Jansma J, Spijkervet FKL, et al. Oral squelae of head and neck radiotherapy. Crit Rev Oral Biol Med 2011:199-212
  7. Susworo R, Meidyawati R, Sasanti H. Penatalaksana anterapi radiasi pada keganasan rongga mulut. JKGUI (Edisi khusus) 2003;10: 989-994.
  8. Toto, Lia Y. Analisis aplikasi konsep gaya dalam fisika yang berkaitan dengan bidang biologi. JPPPF 2017;3: 63-72.
  9. Widyaputra S. Teori molekuler pertumbuhan kanker dan kaitannya dengan peningkatan terapi konvensional. JKG 1998;10: 33-36.
  10. Evans DB, Abbruzzese JLWCG. Cancer of the pancreas. J Pancreas 2011;12: 145-148.
  11. MA CM, Coffey CW, Dewerd LA, et al. AAPM protocol for 40–300 kV X-ray beam dosimetry in radiotherapy and radiobiology. Med Physic 2001;28: 868-893.
  12. Robbins S, Kumar V. Basic Pathology. 9thed. Philadelphia: Elsevier;2013.
  13. Wenzel A. Bitewing and digital bitewing radiography for detection of caries lesions. J Dent Res 2004;83: 72-75.
  14. Beer KT, Zehnder D, Lussi A, et al. Saliva flow pH buffer capacity and colonization by streptococcus mutans during and after radical radiotherapy of head and neck tumours. Otorhino-laringol Nova 2002;3: 137-144.
  15. HornerK, Islam M, FlygareL, etal. Basic principles for use of dental cone beam computed tomography: c onsensus guidelines of the European Academy of Dental and Maxillofacial Radiology. DMFR 2009;38: 187-195.
  16. Redman RS. On approaches to the functional restoration of salivary glands damaged by radiation therapy for head and neck cancer, with a review of related aspects of salivary gland morphology and development. Biotech Histochem 2008;83: 103-130.
  17. Mukhlis S, Amin Z, Ari K. Efektivitas fruit frozen t erhadap keluhan haus dan mulut kering pada pasien CHF yang menjalani program restriksi cairan di ruang UPJ RSUP Dr.Kariadi Semarang. Med Hosp 2014;2: 156-161.
  18. Naumova EA, Gaengler P, Zimmer S, et al. Influence of individual saliva secretion on fluoride bioavailability. 2010;4: 185-190.
  19. Yunus B. The prevalence of Xerostomia after doing radiation therapy in patients with head and neck cancer.J Dentomaxillofac Sci 2017;2: 12-14.

How to Cite

Azhari, A., Hutasoit, Y., Permana, A. C., & Soetopo, S. (2018). Salivary pH changes post nasopharyngeal carcinoma radiotherapy using linac x- ray. Journal of Dentomaxillofacial Science, 3(1), 13–16. https://doi.org/10.15562/jdmfs.v3i1.682
ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver
Download Citation
Endnote/Zotero/Mendeley (RIS) BibTeX

HTML
430

Total
571

Share

Search Panel

Azhari Azhari
Google Scholar
Pubmed
JDMFS Journal

Yohanes Hutasoit
Google Scholar
Pubmed
JDMFS Journal

Ary C. Permana
Google Scholar
Pubmed
JDMFS Journal

Setiawan Soetopo
Google Scholar
Pubmed
JDMFS Journal