Original Article

DOI: 10.15562/jdmfs.v0i0.688

Platelet-rich plasma improves initial bone remodeling

Edy Machmud , Bahruddin Thalib, Mochammad Dharmautama, Acing H. Mude, Irfan Dammar, Muhammad Ikbal

Edy Machmud
Department of Prostodontics, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia. Email: machmudedy@gmail.com

Bahruddin Thalib
Department of Prostodontics, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Mochammad Dharmautama
Department of Prostodontics, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Acing H. Mude
Department of Prostodontics, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Irfan Dammar
Department of Prostodontics, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Muhammad Ikbal
Department of Prostodontics, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
Online First: December 01, 2020 | Cite this Article
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Machmud, E., Thalib, B., Dharmautama, M., Mude, A., Dammar, I., Ikbal, M. 2020. Platelet-rich plasma improves initial bone remodeling. Journal of Dentomaxillofacial Science 5(3): 158-161. DOI:10.15562/jdmfs.v0i0.688


Objective: To compare the osteoblast cell formation process after installation implant with and without added of platelet-rich plasma (PRP). 

Methods: Twenty-four male rabbit were selected by purposive sampling, divide into two groups. Group 1 implant with added PRP were installation in the distal part of the thigh bone 12 male rabbits, Group 2 implants without the addition of PRP mounted on the distal part of the thigh bone 12 male rabbits. All rabbits in euthanasia after 0, 7, 14, and 28 days were then analyzed histologically to determine the formation of osteoblast cells. 

Results: There is increased formation of osteoblast cell formation in implant installation with the addition of PRP when compared with implants without PRP as time increases. 

Conclusion: Administration of PRP in implants can speed up and increase osteoblast cell formation.

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