Skip to main content Skip to main navigation menu Skip to site footer

Pathological fracture of the mandible associated to osteoradionecrosis: a case report

  • Ronal Ronal ,
  • Sylviana Melita ,
  • Syamsuddin Endang ,


Objective: Osteoradionecrosis (ORN) is a severe and devastating late complication of radiotherapy in patients with head and neck cancer, especially in the mandible. Methods: We report a case of a 47-year-old woman who suffering from osteoradionecrosis and bone exposure 5 yearsafter irradiation therapy for Squamous Cell Carcinoma (SCC) of the tounge. Segmented resection of the mandible was performed followed with reconstruction using plate.Results: ORN can cause pathological fracture of the mandible and should be treat with surgical approach Conclusion: ORN affects the mandible more often than the maxilla or any other bones of head and neck, since it has high density and low blood vasculature so can cause pathological fracture of the mandible. Preventive measures must be evaluated to reducing the risk or severity of ORN


  1. Madrid C, Abarca M, Bouferrache K. Osteoradionecrosis: an update. Oral Oncology 2010: 471-474.
  2. Harris M. The conservative management of osteoradionecrosis of the mandible with ultrasound therapy. Br J Oral Maxillofac Surg 1992;30; 313-318.
  3. Lyon A, Ghazali N. Osteoradionecrosis of the jaws: current understanding of its pathophysiology and treatment. British Journal of Oral and Maxillofacial Surgery 2008;46; 653-660.
  4. Fan H, Kim SM, Cho Y J. New approach for the treatment of osteoradionecrosis with pentoxifylline and tocopherol. Biomaterials Research 2014;18: 13.
  5. Jacobson AS, Buchbinder D, Hu K, et al. Paradigm shifts in the management of osteoradionecrosis of the mandible. Oral Oncology 2010;46: 795-801.
  6. Sawhney R, Ducic Y. Management of Pathologic fractures of the mandible secondary to osteoradionecrosis. American Academy of Otolaryngology–Head and Neck Surgery 2012;148: 54-58.
  7. Goyal S, Mohanti BK. Bilateral mandibular fracture related to osteoradionecrosis. Indian J Dent 2015;6; 107-109.
  8. Nadella KR, Kodali RM, Guttikonda LK, et al. Osteoradionecrosis of the jaws: clinico-therapeutic management: a literature review and update. J Maxillofac Oral Surg 2015;14: 891-901.
  9. Zanicotti S, Silvia WPP, Schussel JL, et al. Pathological fracture of the mandible associated to osteoradionecrosis with necrotic bone and reconstruction plate exposure: case report. Chornic Orofacial Pain or Temporomandibular Disorders 2014: 1-3.
  10. Curi MM, Dib LL, Kowalski LP. Management of refractory osteoradionecrosis of the jaws with surgery and adjunctive hyperbaric oxygen therapy. Int J Oral Maxillofac Surg 2000;29: 430-434.
  11. Samad S, Priyanto W. Early treatment of symphysis mandibular fracture in 12 years old children using erich arch bar: a case report. J Dentomaxillofac Sci 2017;2: 58-62.

How to Cite

Ronal, R., Melita, S., & Endang, S. (2020). Pathological fracture of the mandible associated to osteoradionecrosis: a case report. Journal of Dentomaxillofacial Science, 5(3), 200–203.




Search Panel