Journal of Dentomaxillofacial Science https://jdmfs.org/index.php/jdmfs en-US <p>This work is licensed under a <a href="http://creativecommons.org/licenses/by/4.0/" rel="license">Creative Commons Attribution 4.0 International License</a>.</p> jdmfs.fkg@unhas.ac.id (Muhammad Ruslin) arul@discoversys.com (Dr. Arul Kandasamy, PhD) Sat, 30 Dec 2023 09:28:36 +0000 OJS 3.3.0.10 http://blogs.law.harvard.edu/tech/rss 60 Prosthetics management of odonto-onycho-dermal dysplasia pediatric patient: A case report https://jdmfs.org/index.php/jdmfs/article/view/1638 <p><strong>Objective:</strong><span style="font-weight: 400;"> This case report discussed the treatment pediatric patients with OOOD require extensive prosthetic treatment and required collaboration between professionals.</span></p> <p><strong>Methods:</strong><span style="font-weight: 400;"> A 12-year-old male patient was referred from the pediatric dentistry department with complaints that his of teeth had not eruptingerupted after extraction. Intraoral examination showed that only eruptions occurred exclusively in teeth 55,14,24,25,65,32,34,37,42,43,44,47 eruptions. In this case, intraoral and extraoral examinations, radiographs, impressions of the maxillary and mandibular jaws, and denture makingdenture-making procedures (including such as makingthe fabrication of a regular denture) were performed.</span></p> <p><strong>Results: </strong><span style="font-weight: 400;">After 3 months of wearing the removable denture, the maxillary left and right molars were visibly erupted, and the removable denture was then perforated in that area. A month later, the mandibular premolars also erupted, but surgical exposure was performeddone to accelerate the eruption of the teeth.</span></p> <p><strong>Conclusion</strong><span style="font-weight: 400;">: The delayed eruption of teeth in children due to ectodermal dysplasia is a multifaceted condition. Consequently, for optimal results, interdisciplinary therapy is recommended.</span></p> Rifaat Nurrahma, Syakriani Syahrir, Muhammad Ikbal, Edy Machmud, Irfan Dammar, Acing H. Mude, Ike D. Habar, Ludfia Ulfa, Nurimah Wahyuni, Ainun Bazira Copyright (c) 2023 Rifaat Nurrahma, Syakriani Syahrir, Muhammad Ikbal, Edy Machmud, Irfan Dammar, Acing H. Mude, Ike D. Habar, Ludfia Ulfa, Nurimah Wahyuni, Ainun Bazira https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1638 Fri, 01 Dec 2023 00:00:00 +0000 Treatment of mild obstructive sleep apnea using twin block oral appliance https://jdmfs.org/index.php/jdmfs/article/view/1405 <p><strong>Objective: </strong><span style="font-weight: 400;">Obstructive sleep apnea (OSA) is a condition where obstruction of upper airways appears periodically while patient asleep that can be complete (apnea) or partially (hypopnea). This condition is most common on male population with obese body. A prosthodontist can try to help by providing oral appliances (OA) for patient to use while they were asleep. OA were designed to thrust mandible forward and downward so that minimalize the chance for obstruction of upper airways to occur. </span></p> <p><strong>Case Report: </strong><span style="font-weight: 400;">A forty years old patient was complaining about his bad sleep quality. He stated that he often awakens gasping for air while sleeping for almost 3 months, he also stated that he felt exhausted and sleepy during daytime. Patient then prompted to undergo sleep test using home sleep test device ApneaLink Air from Resmed. According to the data gathered by the device, patient was diagnosed having mild sleep apnea and then treated with OA twin block.</span><strong> Result: </strong><span style="font-weight: 400;"> Patient felt improvement on his sleep quality, even though home sleep test while using oral appliance had not been done. </span></p> <p><strong>Conclusion: </strong><span style="font-weight: 400;">Oral appliance can be used to improve patient with mild obstructive sleep apnea sleep cycle.</span></p> Seto Pramudita, Rasmi Rikmasari Copyright (c) 2023 Seto Pramudita, Rasmi Rikmasari https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1405 Fri, 01 Dec 2023 00:00:00 +0000 Fibrin-assisted soft tissue promotion (FASTP) as a simple root coverage technique: A case report https://jdmfs.org/index.php/jdmfs/article/view/1336 <p><strong>Objective:</strong> The objective of this article is to present fibrin-assisted soft tissue promotion (FASTP), a simple root coverage surgical procedure associated with the use of A-PRF as a source of autogenous growth factors that allow the recipient soft tissue to promote the fabrication of new keratinized and attached tissue without a donor site.</p> <p><strong>Methods: </strong>The case&nbsp;of a 20-year-old non-smoker female patient was reported to the Universitas Airlangga Dental Hospital with a chief complaint of tooth hypersensitivity to cold stimuli at the posterior right maxilla and mandibular. A 1–1,5 mm gingival recession was found on the buccal aspect of 14, 15, 44, and 46. A final diagnosis of clinically healthy gingiva on reduced periodontium in a non-periodontitis patient was made. The treatment plan included dental health education with a focus on brushing methods and scaling procedures that were performed as non-surgical therapy. A FASTP procedure was planned for root coverage treatment on the buccal aspect of 14, 15, 44, and 46.</p> <p><strong>Results: </strong>A 1-year evaluation was done and showed complete root coverage with an acceptable gingival phenotype.</p> <p><strong>Conclusion: </strong>FASTP is a simple root coverage surgical technique without the need to harvest tissue from a donor site, thereby decreasing procedure-related morbidity. Case selection plays an important role in proper surgical technique consideration.</p> I-Komang E. Wijaksana, Shafira K. Supandi Copyright (c) 2023 I-Komang E. Wijaksana, Shafira K. Supandi https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1336 Fri, 01 Dec 2023 00:00:00 +0000 Aesthetic rehabilitation on fractured and altered passive eruption anterior teeth: A case report https://jdmfs.org/index.php/jdmfs/article/view/1469 <p style="font-weight: 400;"><strong><em>Objective: </em></strong>This case report aims to present the management of crown fractures with pulpal exposure caused by traumatic injury and a condition called gummy smile or altered passive eruption (APE), through a multidisciplinary approach.</p> <p style="font-weight: 400;"><strong><em>Case Report: </em></strong>A 24-year-old male patient came to the Dental Conservation Clinic RSGM Prof Soedomo FKG UGM, complained of broken teeth and pain in the upper front tooth due to an accident. #12 and #21 experienced horizontal discontinuity to the dentine surface and some lines on the labial surface and #11 underwent a fracture with exposure of the pulpal tissue. The patient wants to take care of broken teeth and improve his smiles.</p> <p style="font-weight: 400;"><em><strong>Results</strong></em><em>: </em>A treatment plan was formulated, which consisted of a stepwise treatment including endodontic treatment, crown lengthening, prefabricated glass-fiber post followed by a core build-up, and finally, direct composite to achieve patient satisfaction.</p> <p style="font-weight: 400;"><strong><em>Conclusion: </em></strong>The careful planning of a multidisciplinary approach such as endodontics, periodontics, and direct restorations can treat patients with complex aesthetic complaints relating to problems with the tooth and its soft tissues, and immediate restoration for providing a fast, predictable, economical, yet satisfactory result to improves patient self-confidence.</p> Rahadyan SJ. Pramudita, Yulita Kristanti, Margareta Rinastiti, Hendargo Pribadi Copyright (c) 2021 Rahadyan SJ. Pramudita, Yulita Kristanti, Margareta Rinastiti, Hendargo Pribadi https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1469 Fri, 01 Dec 2023 00:00:00 +0000 The effect of compression to platelet rich fibrin towards fibroblast proliferation of periodontal ligament: An in vitro study https://jdmfs.org/index.php/jdmfs/article/view/1653 <p style="font-weight: 400;"><strong>Objective: </strong>The aim of this study was to determine the effect of compression to PRF towards the proliferation of periodontal ligament fibroblasts.</p> <p style="font-weight: 400;"><strong>Material and Methods: </strong>In this study, periodontal ligament fibroblasts were divided into four groups: periodontal ligament fibroblasts, periodontal ligament fibroblasts with platelet rich fibrin non-compressed, periodontal ligament fibroblasts with platelet rich fibrin compressed, periodontal ligament fibroblasts with platelet rich fibrin releasate. Each group consisted of 6 samples. The examination of fibroblast proliferation was done using MTT Assay on day 3 and 7.</p> <p style="font-weight: 400;"><strong>Results: </strong>Results were analyzed using ANOVA test followed by post hoc test with at least significant difference. Based on the result, non-compressed PRF showed the highest fibroblast proliferation. It also showed a significant difference between groups of periodontal ligaments, non-compressed PRF and compressed-PRF. Meanwhile, groups of non-compressed-PRF and PRF-releasate showed insignificant difference.</p> <p style="font-weight: 400;"><strong>Conclusion: </strong>The conclusion of this study showed that non-compressed PRF and PRF releasate is more effective to increase the periodontal ligament proliferation.</p> Vincensia M. Karina, Sri P. Lastianny, Soetomo Nawawi Copyright (c) 2023 Vincensia M. Karina, Sri P. Lastianny, Soetomo Nawawi https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1653 Fri, 01 Dec 2023 00:00:00 +0000 Microbial patterns in the operating room and outpatient room (Pedodontic Room) Dental and Oral Hospital Hasanuddin University https://jdmfs.org/index.php/jdmfs/article/view/1651 <p><strong>Objective</strong>: Therefore, researchers want to conduct research to identify microorganisms in the operating room and outpatient room (pedodontic room) of the Dental and Oral Hospital of Hasanuddin University.</p> <p><strong>Material and Methods:</strong> This research uses cross sectional (transversal) design. Total sample is two samples, one sample for outpatient room (pedodontic room) and one sample for the operating room. Sampling using MAS (Microbiological Air Sampler). Samples were calculated using a colony counter then performed gram staining and biochemical tests. Data analysis using univariate analysis.</p> <p><strong>Results</strong>: Airborne bacteria in Pedodontic room is 224 CFU/m<sup>3</sup> and in the operating room obtained an average of 686 CFU/m<sup>3</sup> airborne bacteria. Types of dominant bacteria in the operating room are Sphingomonas paucimobilis, Aeromonas salmonicida, and Alloiococcus otitis, while in the pedodontic room Sphingomonas paucimobilis, Staphylococcus cohnii ssp urealyticus, and Staphylococcus aureus. <strong>&nbsp;</strong></p> <p><strong>Conclusion</strong>: Airborne in the operating room of Dental and Oral Hospital of Hasanuddin University is still contaminated with organism and has not met the minimum standard of bacteria, while the air in the pedodontic room is good and in accordance with the prevailing standards.</p> Abul Fauzi, Hilda R. Liemin Copyright (c) 2023 Abul Fauzi, Hilda R. Liemin https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1651 Fri, 01 Dec 2023 00:00:00 +0000 Infection control and willingness to treat patients with infectious disease; Study of dental students in Aceh, Indonesia https://jdmfs.org/index.php/jdmfs/article/view/1468 <p><strong>Objective:</strong> This study aims to assess dental students’ preparedness for infection control, and willingness to treat patients with or potentially transmit diseases.</p> <p><strong>Material and Methods</strong>: The cross-sectional study was conducted on 121 dental students from the Faculty of Dentistry Universitas Syiah Kuala in 2019. The questionnaire used in previous study in 2017 and consisted of demographic data, preparedness for infection control, and willingness to treat patients with infectious diseases.</p> <p><strong>Results</strong>: There were 121 dental students, the majority are female with one year experience of clinical experience. For infection control preparedness, majority of respondents already do personal protective equipment (64.5%), sterilize instrument before use (74.4%), but for the willingness respondents prefer not to treat patient with transmitted diseases such ad patients with tuberculosis (19.8%), people living with HIV/AIDS (19.8%), Hepatitis C (11.6) and also patient who potentially transmit infection such as sex workers (19.0%) , injecting drug users (19.8%) and LGBT (14%). prefer not to treat patients who potentially transmit infection. Result of the Spearman correlation test, showing infection control has no such correlation with willingness (r &lt;0.15) .</p> <p><strong>Conclusion:</strong> The practice of applying universal precautions has been carried out by respondents, but the levels of students’ willingness to treat patient with infectious disease still very low. It’s necessary to carry out continuing education regarding safety training, so that it can enable dental student to work safely and no longer discriminate against patients.</p> Yuli F. Ossa, Yuniardini S. Wimardhani, Indriasti I. Wardhany Copyright (c) 2023 Yuli F. Ossa, Yuniardini S. Wimardhani, Indriasti I. Wardhany https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1468 Fri, 01 Dec 2023 00:00:00 +0000 The influence of platelet concentrates with and without metronidazole incorporation pre-centrifuge towards periodontal ligament fibroblast proliferation https://jdmfs.org/index.php/jdmfs/article/view/1552 <p><strong>Objective: </strong><span style="font-weight: 400;">Horizontal centrifugation was believed may improve platelet, leukocyte, and growth factors in the buffy coat. Previous study of platelet concentrates metronidazole incorporation was able to greatly inhibit bacteria. Metronidazole might help the proliferation with its ability to inhibit pro-inflammatory cytokines. This study intended to examine the influence of C-PRF and i-PRF with and without metronidazole incorporation horizontal pre-centrifugation towards periodontal ligament fibroblast proliferation.</span></p> <p><strong>Material and Methods: </strong><span style="font-weight: 400;">2x10</span><span style="font-weight: 400;">4</span><span style="font-weight: 400;"> fibroblast cells on the 96 well plates were added with 1 ml of each buffy coat platelet concentrates. The samples were split into five groups: i-PRF, C-PRF, i-PRF metronidazole, C-PRF metronidazole, and control group. Then monitored after 1 day, 3 days, and 5 days using MTT assays. The data were inspected by Two Way ANOVA Test and Post Hoc Test.</span></p> <p><strong>Results: </strong><span style="font-weight: 400;">The result indicated that cell proliferation of fibroblasts was escalated by the addition of C-PRF, i-PRF metronidazole incorporation, and C-PRF metronidazole incorporation group. While the i-PRF group showed decreasing proliferation cell count.</span></p> <p><strong>Conclusion: </strong><span style="font-weight: 400;">This study assumed that platelet concentrates (i-PRF and C-PRF) with metronidazole incorporation can increase the cell proliferation higher than i-PRF and C-PRF only.</span></p> Feby Monika, Ahmad Syaify, Sri P. Lastianny Copyright (c) 2023 Feby Monika, Ahmad Syaify, Sri P. Lastianny https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1552 Fri, 01 Dec 2023 00:00:00 +0000 Antimicrobial activity of chitosan nanoparticles loaded with 0.7% tetracycline against porphyromonas gingivalis https://jdmfs.org/index.php/jdmfs/article/view/1652 <p><strong>Objectives:</strong><span style="font-weight: 400;"> Nanoparticle technology has also come to the fore as a viable drug delivery strategy, providing opportunities for controlled release, protecting the active ingredient from enzymatic or environmental degradation, and local retention. Porphyromonas gingivalis is a Gram-negative obligate anaerobe rod involved in the etiology of periodontal disease. Tetracycline has been widely used as an adjuvant in periodontal therapy due to its antibacterial efficacy of these drugs.&nbsp;</span></p> <p><strong>Material and Methods:</strong><span style="font-weight: 400;"> Samples of this study were the pure culture of P. gingivalis (ATCC 33 277) in Mueller Hinton Agar (MHA). The ionic gelation method made a Chitosan nanoparticle loaded with 0.7% tetracycline. Chitosan nanoparticles loaded with 0.7% tetracycline were directly transferred to the microbiology laboratory to maintain the stability of the material. Mueller Hinton Agar media inoculated with bacteria had holes to input chitosan nanoparticles loaded with 0.7% tetracycline. After repeating these operations four times, the incubator was incubated at 37 ° C for 48 hours. Calipers were used to observe and measure the diameter of the bright zone (clear zone) formed around the hole.</span></p> <p><strong>Results:</strong><span style="font-weight: 400;"> The result shows the potent antimicrobial effectiveness of chitosan nanoparticles loaded with 0,7% tetracycline with an inhibitory zone of 32.8 mm in vitro.&nbsp;&nbsp;</span></p> <p><strong>Conclusion:</strong><span style="font-weight: 400;"> This research has shown a potent </span><span style="font-weight: 400;">antimicrobial activity of </span><span style="font-weight: 400;">chitosan nanoparticles loaded with 0,7% tetracycline against P. gingivalis in vitro.</span></p> Martina Amalia, Irma Ervina, Silvia, Erdi E. Nasution Copyright (c) 2023 Martina Amalia, Irma Ervina, Silvia, Erdi E. Nasution https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1652 Fri, 01 Dec 2023 00:00:00 +0000 Freeze-Dried human platelet-rich plasma effect on osteoblast number and collagen density in periodontitis treatment https://jdmfs.org/index.php/jdmfs/article/view/1316 <p><strong>Objective:</strong><span style="font-weight: 400;"> This study aimed to determine the effect of FD-hPRP on the number of osteoblast and collagen density in periodontitis treatment by a histomorphometric study on oryctolagus cuniculus rabbits' alveolar bone and periodontal ligament. </span></p> <p><strong>Material and Methods:</strong><span style="font-weight: 400;"> Sixteen male rabbits were randomly divided into four groups: Normal; Periodontitis; FD-hPRP; DFDBA. After periodontal surgery by open flap debridement, FD-hPRP was applied in group 3, and DFDBA was applied in group 4. Then all rabbits were decapitated eight weeks after surgery. Histomorphometric analysis calculates the number of osteoblasts and collagen density using image J software. Data were analyzed using one-way ANOVA followed by Post Hoc Least Significant Difference (LSD) test.</span></p> <p><strong>Results:</strong><span style="font-weight: 400;"> The results showed a significant difference (p&gt;0.05) between the periodontitis and FD-hPRP and also DFDBA group. </span></p> <p><strong>Conclusion:</strong><span style="font-weight: 400;"> The application of FD-hPRP effect increases the number of osteoblast and collagen density in periodontitis treatment histomorphometrically in rabbit’s alveolar bone and periodontal ligament.</span></p> Nandini A. Sumitro, Hapsari K. Prathivi, Kwartarini Murdiastuti Copyright (c) 2023 Nandini A. Sumitro, Hapsari K. Prathivi, Kwartarini Murdiastuti https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1316 Fri, 01 Dec 2023 00:00:00 +0000 Detecting children's dental caries risk through finger-digit ratio https://jdmfs.org/index.php/jdmfs/article/view/1647 <p><strong>Objective:</strong>&nbsp;This research aimed to determine whether fingerprints could be used to predict the risk of tooth decay.</p> <p><strong>Material and Methods: </strong>A total of 157 children aged 6 to 12, were included in the study. Their 2D:4D digit ratio was measured using digital calipers. Additionally, intraoral examinations were conducted to assess their caries status using the DMF-T index.</p> <p><strong>Results</strong>: a significant correlation between the digit ratio and the probability of dental caries in children aged 6-12 years at SD Inpres Panaikang. The statistical output shows a positive association between lower digit ratio values and an elevated risk of dental caries. The significance value of the analysis is 0.044, which is below the standard threshold of 0.05.&nbsp;</p> <p><strong>Conclusion</strong>: There is a relationship between the digit ratio (2D: 4D) and the risk of dental caries. Hence, the digit ratio (2D: 4D) can be used to predict the occurrence of caries.</p> Syakriani Syahrir, Andi S. Permatasari, Aini I. Baiduri, Syamsiah Syam, Yayah Inayah Copyright (c) 2023 Syakriani Syahrir, Andi S. Permatasari, Aini I. Baiduri, Syamsiah Syam, Yayah Inayah https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1647 Fri, 01 Dec 2023 00:00:00 +0000 Areca nut cultivators from Tamil Nadu: Is the nut their friend or foe – A questionnaire study https://jdmfs.org/index.php/jdmfs/article/view/1636 <p><strong>Objective:</strong><span style="font-weight: 400;"> The present study was done to evaluate the awareness of people involved in cultivation of areca nut from Tamil Nadu on various oral and systemic health effects of chewing areca nut. </span></p> <p><strong>Material and Methods: </strong><span style="font-weight: 400;">A cross-sectional study was conducted among areca nut cultivators from various districts of Tamil Nadu. People involved in the cultivation of areca nut were included in the study. 500 individuals participated in the study. They were instructed to complete a pre-tested questionnaire with 25 questions. </span></p> <p><strong>Results: </strong><span style="font-weight: 400;">58% of the participants were males and 42% were females. Dryness of the mouth from decreased production of saliva due to areca chewing was known to 57% of the study participants. 39% of the participants were aware of addiction. Oral cancer from areca nut chewing in various forms with/without tobacco was also known to 51% of them. 86% of them were prepared to quit the habit and 92% of them admitted that government has banned the sale of commercial pan masala products. </span></p> <p><strong>Conclusion: </strong><span style="font-weight: 400;">The study evaluated the awareness of oral and systemic effects of chewing areca nut among people involved in cultivation of areca nut from rural parts of Tamil Nadu. Appropriate regulatory measures are critical for educating people from a variety of occupational and socioeconomic backgrounds in both rural and urban areas.</span></p> Vasanthi Vinoth, Kavitha Sanjeev, Ramesh Kumar A., Rajkumar Krishnan, Bose Divya, K Gnanambigai Copyright (c) 2023 Vasanthi Vinoth, Kavitha Sanjeev, Ramesh Kumar A., Rajkumar Krishnan, Bose Divya, K Gnanambigai https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1636 Fri, 01 Dec 2023 00:00:00 +0000 Confidence of clinical year dental students in performing removable denture treatment and their perception of the quality of prosthodontic studies https://jdmfs.org/index.php/jdmfs/article/view/1535 <p><strong>Objective: </strong><span style="font-weight: 400;">To find out the distribution of clinical year students’ confidence to perform prosthodontic treatments and perception towards the quality of prosthodontic studies they have received as a factor that can affect confidence. </span></p> <p><strong>Material and Methods: </strong><span style="font-weight: 400;">Data was collected using online questionnaires and filled out by clinical year students who met the inclusion criteria. Further, the data was grouped according to the year of entrance to the clinical year program in the Faculty of Dentistry Universitas Indonesia. Data was then processed using SPSS version 22 for univariate analysis.</span></p> <p><strong>Results: </strong><span style="font-weight: 400;">This study included 80 respondents. The highest level of confidence were seen when performing removable partial denture treatment (8.29 ± 0.76), try-in stage (wax form) procedure of a removable partial denture (9.00 ± 1.41), and primary impression taking for a complete denture procedure (9.00 ± 1.15). The lowest confidence was seen when performing complete denture treatment (7.08 ± 1,26) and surveying cast for a removable partial denture (6.00 ± 1.41). More than 95% of respondents showed a positive perception towards the quality of prosthodontic studies they received.</span></p> <p><strong>Conclusion: </strong><span style="font-weight: 400;">Most respondents have a positive perception towards the quality of prosthodontic learning at Faculty of Dentistry Universitas Indonesia.</span></p> Ratna S. Dewi, Talitha K. Ardinda, Henni Koesmaningati Copyright (c) 2023 Ratna S. Dewi, Talitha K. Ardinda, Henni Koesmaningati https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1535 Fri, 01 Dec 2023 00:00:00 +0000 RANKL and MMP8 levels in Gingival Crevicular Fluid (GCF) as oral biomarker for periodontal condition https://jdmfs.org/index.php/jdmfs/article/view/1482 <p style="font-weight: 400;"><strong>Objective:</strong> We assessed the diagnostic potential of RANKL and MMP8 in gingivitis and periodontitis patients.</p> <p style="font-weight: 400;"><strong>Material and Methods:</strong> Sixty Seven otherwise gingivitis and periodontitis patient were enrolled at Faculty of Dentistry Universitas Brawijaya and Janti Health Service Malang. Gingival crevicular fluid was sampled modified gingival index include normal (n= 26), mild inflammation (n= 25), moderate (n=10), and severe inflammation (n=6). For periodontitis parameter, GCF was sampled pocket depth such as pocket depth 0-3,5 mm (n= 49), pocket depth 3,6-5,5 mm (n=11), pocket depth &gt;5,5 mm (n=7). RANKL and MMP8 were determined by ELISA (Enzyme-linked immunosorbent assay). Then, One Way ANOVA analysis was used.</p> <p style="font-weight: 400;"><strong>Results:</strong> RANKL showed significantly difference in gingivitis patient (p&lt;0.05), but not periodontitis patient (p&gt;0.05). However MMP8 did not show any significant difference (p&gt;0.05) between gingivitis and periodontitis. RANKL showed a good discrimination performance. RANKL and MMP8 present in the identification of periodontal disease.</p> <p style="font-weight: 400;"><strong>Conclusion:</strong> RANKL presented more accurate diagnostic marker for periodontitis than gingivitis.</p> Ariyati R. Pratiwi, Novi K. Firani; Neny Roeswahyuni, Malianawati Fauziah; Rahmavidy Priyanto Copyright (c) 2023 Ariyati R. Pratiwi, Novi K. Firani; Neny Roeswahyuni, Malianawati Fauziah; Rahmavidy Priyanto https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1482 Fri, 01 Dec 2023 00:00:00 +0000 The effect of non-surgical periodontal therapy on HbA1c levels: A systematic review https://jdmfs.org/index.php/jdmfs/article/view/1648 <p><strong>Objective:</strong> The purpose of the present article is to summarize the evidence present in systematic regarding the non-surgical periodontal therapy effects on HbA1c levels.</p> <p><strong>Methods: </strong>Our study considered the consultation of the bibliographic databases "Medical Systematic Analysis and Retrieval System". The research was carried out by using the keywords: "Diabetes mellitus" AND "Periodontal disease" AND "Scaling and root planing" AND "Non-surgical periodontal treatment" AND "Glycosylated hemoglobin".</p> <p>Our research resulted in 18 articles published between 1995 and 2018.</p> <p><strong>Results: </strong>All studies have shown that periodontal indices have improved after non-surgical periodontal therapy, while the effects on metabolic control are controversial. Some authors find no influence on metabolic variables, others report an improvement. Some studies have used both topical and systemic antibiotics in combination with causal periodontal therapy, observing an improvement in metabolic compensation.</p> <p><strong>Conclusion: </strong>The approach to diabetic patient with periodontitis must be multidisciplinary with close collaboration between periodontists, dental hygienists and endocrinologists.</p> Paolo Boffano, Andrea Melle, Anna M. Agnone, Vincenzo Rocchetti, Muhammad Ruslin Copyright (c) 2023 Paolo Boffano, Andrea Melle, Anna M. Agnone, Vincenzo Rocchetti https://creativecommons.org/licenses/by/4.0 https://jdmfs.org/index.php/jdmfs/article/view/1648 Fri, 01 Dec 2023 00:00:00 +0000